Ziyuglycoside I
Ziyuglycoside I
CAS: 35286-58-9
Molecular Formula: C41H66O13
Ziyuglycoside I - Names and Identifiers
Ziyuglycoside I - Physico-chemical Properties
| Molecular Formula | C41H66O13 |
| Molar Mass | 766.95 |
| Density | 1.35 |
| Melting Point | 198-202 ºC |
| Boling Point | 841.9±65.0 °C(Predicted) |
| Specific Rotation(α) | (c, 2.5 in Py)+18 |
| Solubility | Soluble in methanol, DMSO and other solvents, insoluble in petroleum ether, chloroform. |
| Appearance | White crystal |
| pKa | 12.52±0.70(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD13195536 |
| Physical and Chemical Properties | White crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Sanguisorba. |
Ziyuglycoside I - Reference
| Reference Show more | 1. Tang Jun Zhang Jie Sun Wei Zhao Ang Zhu Zhiming Bao Xiao Wen Zhang Ming Ya Ma Bo. Simultaneous determination of Sanguisorba officinalis saponin Ⅰ and Sanguisorba officinalis saponin Ⅱ in rat plasma by LC-MS/MS and its pharmacokinetics [J]. Bioprocess 2019 17(05):536-541. 2. [IF = 3.935] Li Li et al."Rapid identification of urokinase plasmin activator inhibitors from Traditional Chinese medicine based on ultrafiltration, LC-MS and in silico docking."J Pharmaceut Biomed. 2019 Feb;164:241 3. [IF=4.36] Hanfei Sun et al."Ziyuglycoside I attenuates collagen-induced arthritis through inhibiting plasma cell expansion."JOURNAL OF ETHNOPHARMACOLOGY. 2022 Aug;294:115348 |
Ziyuglycoside I - Reference Information
| Overview | Sanguisorba officinalis saponin I, English name ziyu-glycoside I, it is a compound with obvious pharmacological activity extracted from the root of Sanguisorba or Sanguisorba longicidae. |
| biological activity | Ziyuglycoside I from S. Isolated from the roots of officinalis, has anti-wrinkle activity and increases the expression of type I collagen. Ziyuglycoside I is useful as an active ingredient in cosmetics. Ziyuglycoside I induces p53-mediated cell cycle arrest and apoptosis, which can be used in the study of triple negative breast cancer. |
| Cell Line: | MDA-MB-231 cells MDA-MB-231 cells MDA-MB-231 cells |
| Concentration: | 5 µM, 10 µM, 20 µM, 40 µM, 80 µM, and 160 µM 5 µM, 10 µM, and 20 µM 5 µM, 10 µM, and 20 µM |
| Incubation Time: | 24 hours 24 hours 24 hours |
| Result: | Showed cytotoxicity on MDA-MB-231 cells. Induced G2/M phase arrest and apoptosis on MDA-MB-231 Cells Induced apoptosis in MDA-MB-231 Cells through Intrinsic and Extrinsic Pathways. |
| Use | Sanguisorba officinalis saponin I has vasoconstrictive, hemostatic and antifungal effects. for content determination/identification/pharmacological experiments. Pharmacological Efficacy: has a certain liver choleretic effect. |
Last Update：2024-04-09 20:45:29
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Mobile: 18021002903
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